A new human blood group—CRIB
Kartavya Desk Staff
Source: TN
Context: A new human blood group—CRIB—has been discovered at the Rotary Bangalore TTK Blood Centre. It is the first of its kind globally, officially recognised by the International Blood Group Reference Laboratory (IBGRL), UK.
About A new human blood group—CRIB:
• What is CRIB Blood Group? CRIB stands for Cromer India Bengaluru. It is a new antigen identified within the Cromer (CR) blood group system, not previously observed in any human sample worldwide. Discovered in a 38-year-old South Indian woman undergoing cardiac surgery in Kolar, Karnataka.
• CRIB stands for Cromer India Bengaluru.
• It is a new antigen identified within the Cromer (CR) blood group system, not previously observed in any human sample worldwide.
• Discovered in a 38-year-old South Indian woman undergoing cardiac surgery in Kolar, Karnataka.
• How was it Identified? The woman’s blood tested panreactive—meaning it reacted with all tested samples and was incompatible even with O+ blood. No compatible match was found among 20 family members Sample was sent to IBGRL, UK, where after 10 months of molecular analysis, the new antigen was confirmed and officially named CRIB.
• The woman’s blood tested panreactive—meaning it reacted with all tested samples and was incompatible even with O+ blood.
• No compatible match was found among 20 family members
• Sample was sent to IBGRL, UK, where after 10 months of molecular analysis, the new antigen was confirmed and officially named CRIB.
• Scientific Significance: CRIB is now a new entry in global transfusion medicine. Named using standard ISBT nomenclature. Adds to India’s contribution in rare blood immunogenetics. Highlights the need for rare donor registries and global collaboration in blood typing.
• CRIB is now a new entry in global transfusion medicine.
• Named using standard ISBT nomenclature.
• Adds to India’s contribution in rare blood immunogenetics.
• Highlights the need for rare donor registries and global collaboration in blood typing.
• What is the Cromer Blood Group System? Cromer system is a rare blood group classification involving antigens located on the DAF (Decay-Accelerating Factor) protein on red cells. These antigens are important in immune reactions during transfusion.
• Cromer system is a rare blood group classification involving antigens located on the DAF (Decay-Accelerating Factor) protein on red cells.
• These antigens are important in immune reactions during transfusion.